This week’s 49ers mailbag is stocked with questions (and answers) regarding their offensive shortcomings, fourth-quarter ...

Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

At linebacker, Dee Winters had his best game of the season while Kyle Shanahan provided a rough timeline for Dre Greenlaw's ...

San Francisco 49ers head coach reveals Deebo Samuel is dealing with a tough condition. Kyle Shanahan says there's no timeline ...

Even with those ailments of the team’s top three offensive players, the Niners are sizable favorites over the Dallas Cowboys ...

Coach Kyle Shanahan said tests Monday confirmed the initial diagnosis Aiyuk tore his ACL and would need major reconstructive ...

San Franciscco 49ers head coach Kyle Shanahan revealed that star receiver Deebo Samuel Sr. is currently hospitalized with pneumonia and fluid in his lungs after trying to play against the Kansas City ...

The Seattle Seahawks could potentially be without their star wide receiver D.K. Metcalf for some time. Metcalf landed hard after going up for a pass in the Seahawks' 34-14 win over the Atlanta Falcons ...

The Cowboys have shown a capability of turning things around after a bye week under McCarthy. They are 3-1 after the bye week ...

The strength of the San Francisco 49ers’ offense the past few seasons has been the number of dynamic playmakers that makes it ...

This is something to monitor. George Kittle apparently sprained his foot during the 49ers' 28-18 loss to the Kansas City ...

Following the significant losses of players due to injury and illness, including Brandon Aiyuk, San Francisco 49ers head ...