ACR20 response rates were significantly greater in tofacitinib treatment versus placebo at 5 mg bid (RR 2.20; 95% CI 1.58, 3.07) and 10 mg bid (RR 2.38; 95% CI 1.81, 3.14) after 12 weeks of treatment.

All patients were female and the average age at diagnosis was 10.67 years. At initiation of ... mg qd), HCQ (100 mg bid), Cys A (morning: 50 mg, evening: 25 mg), belimumab (480 mg q4w IV). Reason for ...

Patients were eligible if they had glucocorticoid dependence (inability to successfully taper to <10 mg per day of prednisone ... Janus kinase inhibitors [tofacitinib, upadacitinib, or filgotinib ...

The alanine aminotransferase level was 57 U per liter (normal range, 10 to 50), and the albumin ... of inflammatory markers while taking 22 mg of tofacitinib and a reduced dose of 8 mg of ...

Results from the national "Urgent Conversations" survey, announced today by Eli Lilly and Company (NYSE: LLY), found that ...

After randomisation, either a dosage of tofacitinib 5 mg two times a day or 5 mg per day was administered ... Briefly, the study was powered to detect a 10% difference in sustained remission rates at ...

Eight articles used funnel plots to test for publication bias, while the remaining ten did not, resulting in a rank of 10 for ... at 15 mg resulted in significantly improved ACR20/50/70 indicators ...

Stable background treatment of non-steroidal anti-inflammatory drugs, corticosteroids (equivalent to ≤10 mg/day prednisone) and ≤2 non-biologic DMARDs were permitted; background therapy was not ...

In subsequent JAKi treatment, 28% (7/25) used tofacitinib, and 72% (18/25) used ruxolitinib. In patients of <25 kg (n=11), the initial dosage was 2.5 mg twice daily ... decreased dramatically from 7.0 ...

We undertook a rigorous systematic review and meta-analysis using independent reviewers for data extraction and statistical analysis. To our knowledge, this is the first systematic review of the ...

Systemic JAK inhibitor therapy with tofacitinib was associated with the most favorable outcomes among patients with extensive vitiligo.

Your browser does not support the audio element. JSW MG Motor India recently announced an all-new retail channel called MG Select for its more premium offerings ...