Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...
Some key published and presented research findings include: Adoptive T cell receptor (TCR ... a second CAR molecule improved tumor specificity and enhanced NK cell activity Adding CD28 costimulation ...
Members of Medigene management as expert speakers, Prof. Dolores Schendel, Chief Scientific Officer and Kirsty Crame, MD, Vice President, Clinical Strategy & Development Presentations and seminars ...
The in vivo cell therapy seed Carisma Therapeutics planted with Moderna in 2022 is starting to sprout. | The in vivo cell ...
Preclinical proof-of-concept data supports the potential of CD3 Switch-DARPin platform to activate and boost T cells in the presence of tumor ...
VANCOUVER, British Columbia, November 07, 2024 -- ( BUSINESS WIRE )-- AbCellera (Nasdaq: ABCL) today announced new data on ...
AbbVie has entered into a partnership and option-to-license agreement with EvolveImmune Therapeutics, to develop ...
AbbVie’s deal team is having a busy week. Days after inking a $1.4 billion buyout, the drugmaker has put up the same again in biobucks to secure options on multispecific T-cell engagers from ...
MacMaster, Ph.D., associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment ...
1 Racah Institute of Physics, The Hebrew University, Jerusalem, Israel 2 School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel T cells respond swiftly, ...
While therapeutic antibodies targeting these inhibitory receptors can sustain T cell function, recent studies have underscored the importance of positive costimulation in limiting the development of ...