This is the first study linking NF-κB signaling pathways ... signaling occurs downstream of T cell receptor engagement, which ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

Most cell signals ... in intracellular signaling pathways. Specifically, the addition of phosphate groups causes a conformational change in the enzymes, which can either activate or inhibit ...

The process of T-cell activation requires at least two signals. [14] The first signal is antigen-specific ... as well as a number of other pathways or mediators central to initiation and ...

University of Bonn researchers developed a new technique to study immune cell receptors ... to be very familiar with the ...

AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

New study of ‘immune memory’ and T-cells has the goal of coming up with the next wave of immunotherapy, UCSD researcher says ...

Neuroscientists have uncovered a mechanism that controls the reactivation of neural stem cells ... and the Hippo pathway are highly conserved in humans, our findings aren't just relevant for ...

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...

Neural stem cells (NSCs) are important for ... “Given that SUMO proteins and the Hippo pathway are highly conserved in humans, our findings aren’t just relevant for fruit flies,” said ...

This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...