In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.

A novel lentiviral packaging system enables production from a single-plasmid transfection instead of the standard four-plasmid process.

Scientists are testing CRISPR gene editing as a potential HIV cure after successfully removing the virus from infected cells ...

A systematic review of more than 200 studies published in BMC Infectious Diseases on human viruses over more than a century ...

But in the 1990s the virus that causes AIDS turned out to offer a solution. Researchers discovered how to strip away HIV’s destructive genes and repurpose it as a “lentiviral vector”—a tool to deliver ...

Human immunodeficiency virus (HIV) infections are still fairly common and an estimated 40 million people worldwide are currently living with this condition. The HIV virus attacks the body's immune ...

After receiving a series of immunotherapies, most people with HIV in a small study kept their virus levels low for several months—and one person for more than a year and a half—without their usual ...

A man has become the seventh person to be left HIV-free after receiving a stem cell transplant to treat blood cancer. Significantly, he is also the second of the seven who received stem cells that ...

People infected with HIV must take antiretroviral drugs for life. But engineered antibodies appeared to suppress the virus for certain participants in recent trials in Africa and Europe A digital ...

Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, researchers have now identified a perineural pathway through which the HIV virus ...

A groundbreaking discovery reveals how HIV integrates its genetic material into human DNA, exposing a key viral vulnerability that could lead to new therapies and bring the world closer to a ...