Results from these trials are expected to define the therapeutic effects of TX45 and enable us to understand its potential role in the treatment of patients with PH-HFpEF.” About the APEX Phase 2 ...

Risk for heart failure events is decreased and health status is improved in patients with HFmrEF and HFpEF receiving finerenone.

In a report released on November 8, David Risinger from Leerink Partners maintained a Buy rating on Tectonic Therapeutic (TECX – Research ...

For patients with HFPEF and other underlying comorbidities, such as diabetes or coronary artery disease, treatment with an ACE inhibitor is nonetheless beneficial. The theoretical benefits of ACE ...

a cardiac myosin inhibitor with a mechanism of action distinct from aficamten for the potential treatment of heart failure with preserved ejection fraction (HFpEF), and CK-089, a fast skeletal muscle ...

Although finerenone has kidney protective effects in patients with chronic kidney disease and type 2 diabetes, it does not appear to slow kidney function decline in patients with heart failure with ...

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"We have four pillars of guideline-directed medical therapy in HFrEF, but only SGLT2 inhibitors as a treatment option for HFmrEF/HFpEF," he said. "Given that finerenone was beneficial in patients ...

Welcome to the third-quarter 2024 Novo Nordisk A/S earnings conference call. [Operator instructions] Please be advised that ...

Medically reviewed by Anisha Shah, MD Congestive heart failure (CHF) occurs when your heart muscles become damaged and can't ...

Treatment with tirzepatide reduced the risk ... A key difference between SUMMIT and Novo Nordisk's STEP-HFpEF study of semaglutide is that it included hard cardiovascular outcomes as the primary ...