Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...

Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...

All these applications are expected to revolutionize the early ... Mechanisms of EV biogenesis in cancer cells and their cargo selection. • The interplay between EVs and tumour microenvironment ...

CAR-T cell therapy, a marvel of bioengineering, takes a patient’s own immune cells and reprograms them to attack cells ...