The new body-horror movie "The Substance" is a wild time, It also took co-stars Demi Moore and Margaret Qualley way out of their comfort zones.

Demi Moore tells PEOPLE she hadn't met Margaret Qualley before becoming her costar in Coralie Fargeat’s new horror movie 'The Substance,' but had enough 'indirect connections' that they 'felt like we

"The Substance" is a dark modern fable that starts out blaming men for reducing women to sex objects and then cuts deeper. Fargeat saves a special rage for women who conspire in their own diminishment, trading their soul in a pulse beat for a few more shining hours as a goddess.

In its first two hours, “The Substance” is a well-made, entertaining movie. Writer-director Coralie Fargeat treats audiences to a heavy dose of biting social commentary on ageism and sexism in Hollywood, with a spoonful of sugar- and sparkle-doused body horror.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

The body horror nightmare story is sensual, unhinged, grotesque, and will have you howling with laughter. Demi Moore has never been better.

She and costar Margaret Qualley also devoted time to perfecting sexualized gyrations their celebrity fitness characters would perform in front of leering cameras and a slimeball of a boss, played by Dennis Quaid,

The Substance, the new film starring Margaret Qualley and Demi Moore, has set a record for the latter. The body-horror film follows a fading celebrity (played by Moore) who begins to use a black-market drug that creates a younger version of herself (Qualley).

Margaret Qualley costars in this gory — like, really gory! — satire about beauty and aging The Substance, a corrosively vicious horror satire with a career-resuscitating turn by Demi Moore, begins with an inspired if not very kind joke: You’re looking down the Hollywood Walk of Fame as a fresh,