The new study demonstrated the role of the NF-κB pathway in regulating ... of X chromosome inactivation after T cell activation requires NF-κB signaling, Science Immunology (2024).

Most cell signals ... in intracellular signaling pathways. Specifically, the addition of phosphate groups causes a conformational change in the enzymes, which can either activate or inhibit ...

Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular proteins, such as those from bacteria, in order to activate an ...

Lyell Immunopharma, Inc.'s strong financials, innovative CAR T-cell therapies, and strategic acquisitions position it for ...

AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

New study of ‘immune memory’ and T-cells has the goal of coming up with the next wave of immunotherapy, UCSD researcher says ...

Neuroscientists have uncovered a mechanism that controls the reactivation of neural stem cells ... and the Hippo pathway are highly conserved in humans, our findings aren't just relevant for ...

This valuable study provides solid support for the participation of the BMP-binding domain of MuSK, a tyrosine kinase mostly known for its role at the neuromuscular junction, in the maintenance and ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in ...

Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies ...

This is the first study linking NF-κB signaling pathways ... signaling occurs downstream of T cell receptor engagement, which ...