HF with preserved ejection fraction is recognized as a major contributor to CV morbidity and mortality and a growing health problem worldwide.The prevalence of HF with preserved EF (HFpEF) is ...

Regardless of ejection fraction, including those with EF > 55%, I would give empagliflozin to all HFpEF patients.” Cardiologists need to rethink how they approach the newer medications, Lala ...

Among patients with heart failure with preserved ejection fraction (HFpEF), lower versus higher ranges of EF signal fundamentally different morphologies and hemodynamic responses, which may have ...

So, your patient has shortness of breath. The echo shows an EF of 50%. How do you know it's HFpEF? What do you need to exclude? What treatment strategies are beneficial?

While those below the median of 56% EF had a spironolactone benefit with a hazard ratio of 0.78 (P=0.02), there was a nonsignificant interaction term for treatment effect by EF (P=0.22).

A study challenges the dogma of beta-blockers for HF with preserved ejection fraction. For now, the strategy might only be for HFpEF patients already with pacemakers.

Though the trial was billed as including a HFpEF population, it included some patients with EFs of 41% to 49%, which was previously defined as midrange but is now classified as “mildly reduced” EF in ...

Among EMBARK-HFpEF participants, there was a significant 3.2-percentage point absolute LVEF reduction. Although there were no deaths or drops in LVEF below 30%, six of the 30 patients discontinued ...

A total of 92 patients with HFpEF (EF ≥ 45%) admitted to a university hospital in Japan between 2015 and 2018 were included in the study.

But when older adults develop heart failure they more often have a normal EF of 50% or greater, called heart failure with preserved ejection fraction (HFpEF). With HFpEF, the left ventricle muscle ...