Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...

T cells in patients with relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL). T-ALL, known for its challenging ...

Patients with abnormal numbers of CD3 + T cells had considerably higher mortality and recurrence rates. The immune system and especially the B cells of patients with acute lymphoblastic leukemia (ALL) ...

"We found ASXL1 mutated in the T cells of all of those patients and decided to investigate further." "We showed Asxl1 disruption endows T cells with superior long-term therapeutic potential ...

CAR-T cell therapy, a marvel of bioengineering, takes a patient’s own immune cells and reprograms them to attack cells ...

Why don't we realize resolutions within a biomolecule?" Because until now, detecting nanometer distances between two proteins, or their subunits, has been the prerogative of a method termed Förster ...

The type of ALL you’re diagnosed with depends on the primary lymphocytes involved, B cells or T cells, and their genetic features. ALL is not a common cancer, but it’s the most common ...

Fundamental research on clinical challenges has the potential to broaden our view of diseases such as B-ALL and other related illnesses, like B-cell chronic leukemia and T-cell leukemia ...

Department of Physiology, Division of Life Science, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan ...

Spurred by advances in energy-harvesting materials, a new generation of advanced implantable biomedical devices is emerging ...