Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...

Patients with abnormal numbers of CD3 + T cells had considerably higher mortality and recurrence rates. The immune system and especially the B cells of patients with acute lymphoblastic leukemia (ALL) ...

UC San Francisco treated its first brain cancer patient with an experimental new CAR-T therapy discovered and manufactured at ...

The improvements persisted in all but one recipient, who showed slight reversals during a one-year observation period. Bharti ...

CAR-T cell therapy, a marvel of bioengineering, takes a patient’s own immune cells and reprograms them to attack cells ...

With a median follow-up of 18.97 months (95% CI, 0.43-72.11), the median OS among all patients was 18.23 months (95% CI, 7.79 ...

Since the current outbreak of mpox clade I began in eastern DR Congo in 2023, there has been a rapid increase in cases, primarily in DR Congo, and spread of the monkeypox virus to other countries in ...

All these applications are expected to revolutionize the early ... Mechanisms of EV biogenesis in cancer cells and their cargo selection. • The interplay between EVs and tumour microenvironment ...