Open Heart

From structural heart lesions to host burden: changing epidemiology and outcomes of native valve infective endocarditis, a nationwide study, 2006–2023

Background The epidemiology of native valve infective endocarditis (IE) has shifted toward older adults with substantial ...

Krystal Biotech, Inc.: Krystal Biotech Announces Positive Interim Clinical Update from KB407 Phase 1 CORAL-1 Study with Confirmation of Wild-Type CFTR Delivery to the Lungs of ...

Confirmed wild-type CFTR delivery and expression in conducting airway cells of patients with class I mutations KB407 transduction confirmed in all six patients with successful bronchoscopies irrespect ...
Kauppalehti

O3R-5671 Pharmacokinetic and Pharmacodynamic Data to be Presented at ECCO and Dosing in Final Cohort in First-in-human study initiated

In addition, Onco3R announced that dosing in the final cohort of the first-in-human study of O3R-5671 has been initiated. The pharmacokinetic (PK) data generated in the first-in-human study ...