Alternatively, interested persons may submit comments, identified by docket number EERE-2025-BT-STD-0038 and or regulatory identification number (RIN) 1904-AG03, by any of the following methods: (1) ...

The development of RI-AG03 represents more than just a potential treatment for Alzheimer’s. It opens up new avenues for drug discovery in the broader field of neurodegenerative diseases.

“RI-AG03 is specifically designed against the Tau protein, meaning it’s less likely to undesirably interact with other proteins,” says Aggidis. While these results, published in the journal ...

The RI-AG03 drug was produced using computational biology techniques to specifically target both fibril zones on the tau protein. The effectiveness it has shown in these experiments are evidence of a ...

A team of international researchers has found a promising new drug candidate for the treatment of Alzheimer’s disease. The scientists say they have developed a peptide inhibitor called RI-AG03 ...

They found that RI-AG03 penetrated the cells and reduced the aggregation of tau proteins, too. "What is new here, is that the authors have invented a molecule that binds to both tau hotspot regions.

The increasing knowledge on how protein tau is organized in live cells has shown that the protein forms nanometer-sized hotspots which are different from tau microtubules. These hotspots, essential ...

“RI-AG03 is specifically designed against the tau protein, meaning it’s less likely to undesirably interact with other proteins,” said Aggidis. An important step toward creating treatments that can ...

Study found that the medication, called RI-AG03, was effective at preventing the buildup of Tau proteins Nina Massey Thursday 03 October 2024 15:59 BST ...

Now, an international team led by Lancaster University in the UK says it has developed a drug called RI-AG03 that targets and blocks the two “hot spots” where tau clumping tends to occur.

RI-AG03 is specifically designed against the Tau protein, meaning it’s less likely to undesirably interact with other proteins.” Research Testing and Outcomes To test its effectiveness in cells within ...