Thyrotropin-releasing hormone (TRH) is a small yet highly significant tripeptide consisting of the amino acids pyroglutamate, histidine, and proline. First identified in the hypothalamus, TRH was ...
We report on a family with recessive resistance to the action of thyrotropin-releasing hormone (TRH) due to a nonsense homozygous mutation in the TRH receptor (TRHR) gene (p.R17X). We examined the in ...
Regulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypothalamus (the region of the brain that controls the involuntary nervous ...
These biochemical and radiological investigations were consistent with the diagnosis of a TSHoma. The patient declined medical or surgical treatment and has remained clinically euthyroid during 4 ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 74, No. 8 (Aug., 1977), pp. 3579-3581 (3 pages) Material reacting with an antibody to thyrotropin-releasing ...
In patients with amenorrhea and infertility, increased levels of serum luteinizing hormone and follicle-stimulating hormone are usually due to primary gonadal failure, whereas a selective increase in ...