The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...
New research has shown that Sonic Hedgehog (SHH)–Gli1 signaling in microglia amplifies inflammatory responses through the IKKβ/NF-κB pathway, contributing to dopaminergic neuron loss in Parkinson’s ...
A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...
A new study from Malave et al. suggests that in the brains of L-Dopa-treated Parkinson’s patients the lack of Shh signaling to cholinergic neurons results in L-Dopa induced dyskinesia. Image credit: ...
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