On April 9, 1982, a doctor at the University of California, San Francisco, published a paper in the journal Science showing ...

Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Case Western ...

Abnormal prion proteins are little understood disease agents involved in causing horrific brain-wasting diseases such as Creutzfeldt-Jacob disease in people, mad cow disease in cattle and chronic ...

We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...

The virus causing the ongoing COVID-19 pandemic, SARS-CoV-2, has spread far more quickly than any other coronavirus in recorded history. Why is it so contagious? One possibility is that its spike ...

The misfolding of proteins and their subsequent deposition as amyloid in peripheral nerves lead to sensory and autonomic neuropathy A new hereditary form of neuropathy, prion protein (PrP) systemic ...

A molecular Dr. Jekyll finally has a day job—as an electrical lineman. A new study suggests that the normal form of prion protein helps maintain the insulation that speeds electrical signals along ...

He flicked on his headlamp, startled to find that the liquid was blood, and a vampire bat—a species he had gone there to ...

Chronic wasting disease (CWD) is a contagious neurological disorder that affects deer, elk, reindeer, and moose that leads to degeneration of brain tissue. Symptoms in infected animals include ...