Touch a hot plate and your hand flies back. While the response is almost instant, researchers are still working to better understand the molecular mechanisms behind these sensations of heat and pain.

Before being discontinued, the P2X7 receptor blocker had cleared a master protocol study in chronic pain, though Eli Lilly ...

They’re growing miniature 3D brains from stem cells. These aren’t your fictional mad scientists’ brains in a vat; they’re ...

The endocannabinoid system is the body’s system that regulates an array of other systems in the body. It works to maintain homeostasis by the use of receptors, cannabinoids, and metabolic pathways ...

Treating mice with a molecule that rescued autophagy and balanced neuronal excitability reduced pain behaviors, offering a ...

Nobody likes to feel pain, but it’s something every person will experience at some point in their life. But why is that? I am a neuroscientist, and my job is to research why and how people feel pain ...

Sometimes pain is a necessary warning signal; for example, if we touch something very hot and it burns, we know to move our hand away. But chronic pain can destroy a person's quality of life, and it ...

This is big news for Irritable Bowel Syndrome (IBS) patients: 11 percent of the world's population suffers from IBS, but the fight against chronic pain has taken a major step forward with scientists ...

Removing human pain receptors could end chronic suffering but might reduce life expectancy, as pain serves as a vital signal ...

A new opioid-free pain medication was approved by the U.S. Food and Drug Administration (FDA) on Thursday, marking a non-addictive alternative for patients. Journavx (suzetrigine), made by Vertex, is ...