Week 7 in the NFL had 12 games on Sunday, starting and ending with the NFC West. It started with the final London game of the year with the LA Rams blowing out the Jacksonville Jaguars. It ended with the San Francisco 49ers beating the Atlanta Falcons on Sunday Night Football.

In a head-to-head meeting of the NFL's top two backs in yards from scrimmage, McCaffrey helped the 49ers beat the Falcons and Bijan Robinson. He rushed for 129 yards and both touchdowns in the 49ers' 20-10 win and also led the team with seven catches for 72 yards. That puts him at an NFL-best 981 yards from scrimmage.

RB  Josh Jacobs  ' status for Sunday's game against the Cardinals is up in the air as he deals with an illness and a calf strain, and whether he plays or not will be determined pregame, NFL Network Insiders Ian Rapoport and Tom Pelissero reported.

Let's dive into all three prime-time matchups, and the most intriguing games in the early and late Sunday afternoon windows.

It solidified an MVP campaign for one running back, the Indianapolis Colts’ Jonathan Taylor, and furthered impressive early-season turnarounds for the Chicago Bears, who are now riding their longest win streak since 2018, and the Carolina Panthers, who are above .500 for the first time in four long years.

Watch New Orleans Saints wide receiver Chris Olave's Week 7 highlights as he gained 98 yards and caught a pair of touchdowns against the Chicago Bears during the 2025 NFL season. Check out the game action photos from the New Orleans Saints game against the Chicago Bears for Week 7 of the 2025 NFL season on Oct. 19, 2025 at Soldier Field.