Mastocytosis is a group of rare haematological disorders characterised by an abnormal accumulation of clonal mast cells in the skin or other organs, particularly the bone marrow. The condition ...

Blueprint Medicines, a Sanofi company, today announced AYVAKIT® (avapritinib) data showing clinically meaningful outcomes and ...

AYVAKIT ® (avapritinib) is a prescription medicine used to treat adults with indolent systemic mastocytosis (ISM). AYVAKIT is ...

The National Institute for Health and Care Excellence has recommended avapritinib (Ayvakyt) as a treatment option for adults with advanced systemic mastocytosis. Mastocytosis is a rare group of ...

Advanced systemic mastocytosis (advSM) is a rare and serious form of systemic mastocytosis, a blood disorder that involves the overproduction of mast cells. Mast cells are a type of white blood cell ...

Reference ranges for basal serum tryptase (BST) are an excellent guide to determining whether a patient’s BST value is normal, per their specific tryptase genotype. If the BST is elevated based on the ...

—An analysis of registry data concluded that hypersensitivity reactions in patients with mastocytosis are caused by exposure to certain triggers, including low tryptase levels and stings from certain ...

Adam Feuerstein is a senior writer and biotech columnist, reporting on the crossroads of drug development, business, Wall Street, and biotechnology. He is also a co-host of the weekly biotech podcast ...

In the complex world of rare diseases, even small advances in understanding can make a profound difference in patients’ lives. Medscape Live is bringing back-to-back educational programs to San Diego ...