STATEN ISLAND, N.Y. -- There is a connective tissue disorder that affects the bones, skin, lungs, heart, blood vessels and nervous system of one in every 5,000 Americans: Marfan syndrome. Members of ...

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which has no cure to date. This disease ...

Marfan syndrome affects the body’s connective tissues, which hold cells, organs and tissues together. They are also important in the the body’s growth and development. Some characteristics are evident ...

Angiotensin receptor blockers (ARBs) and beta-blockers have similar and independent effects on reducing aortic root size in patients with Marfan syndrome, suggesting that several years of combined ...