The NMDA receptor, a brain protein crucial for learning and memory, can function as a "frequency discriminator," translating stimulation frequency into current amplitude and possibly deciding whether ...

The difference between mental health and mental illness can turn on changes in brain cells and their connections that are almost incomprehensibly tiny, at least in physical terms. This irony is ...

Elaine C. Budreck, Oh-Bin Kwon, Jung Hoon Jung, Stephane Baudouin, Albert Thommen, Hye-Sun Kim, Yugo Fukazawa, Harumi Harada, Katsuhiko Tabuchi, Ryuichi Shigemoto, Peter Scheiffele, Joung-Hun Kim ...

A research team has identified a molecular mechanism that coordinates the operation of the N-methyl-D-aspartate (NMDA) glutamate receptor, which is key to regulating excitatory synapse function in the ...

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in ...

Two new publications add to growing evidence that toxic Aβ oligomers play havoc with neurons by interfering with N-methyl-D-aspartate (NMDA)-type glutamate receptors (NMDARs) and Ca2+ flow, but they ...

A scientific study describes that GluN3A subunits of NMDA receptors that interact with glutamate —the main exciting neurotransmitter in the nervous system— are therapeutic targets against Huntington's ...

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in ...

The FDA approved combination dextromethorphan and bupropion extended-release tablets (Auvelity) for adults with major depressive disorder (MDD), Axsome Therapeutics announced on Friday.

The N-methyl-D-aspartate receptors (NMDAR) are cation channels in the brain that play important roles in the transmission of nerve impulses and neuronal plasticity. These ligand-gated channels have ...