The NMDA receptor, a brain protein crucial for learning and memory, can function as a "frequency discriminator," translating stimulation frequency into current amplitude and possibly deciding whether ...

Elaine C. Budreck, Oh-Bin Kwon, Jung Hoon Jung, Stephane Baudouin, Albert Thommen, Hye-Sun Kim, Yugo Fukazawa, Harumi Harada, Katsuhiko Tabuchi, Ryuichi Shigemoto, Peter Scheiffele, Joung-Hun Kim ...

Two new publications add to growing evidence that toxic Aβ oligomers play havoc with neurons by interfering with N-methyl-D-aspartate (NMDA)-type glutamate receptors (NMDARs) and Ca2+ flow, but they ...

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in ...

A scientific study describes that GluN3A subunits of NMDA receptors that interact with glutamate —the main exciting neurotransmitter in the nervous system— are therapeutic targets against Huntington's ...

According to an article in the January 14 Cell Reports, boosting the activity of certain excitatory receptors in the brain calms epileptic activity and improves learning and memory in mouse models of ...

The FDA approved combination dextromethorphan and bupropion extended-release tablets (Auvelity) for adults with major depressive disorder (MDD), Axsome Therapeutics announced on Friday.

The N-methyl-D-aspartate receptors (NMDAR) are cation channels in the brain that play important roles in the transmission of nerve impulses and neuronal plasticity. These ligand-gated channels have ...

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In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers. One of the biggest problems with any type of cancer is metastasis; and ...