As a lab within the Cooperative Center of Excellence in Hematology (CCEH) at Fred Hutch, the Vector Production core assists investigators with the design, construction, and/or production of viral ...
Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...
Two general strategies are being developed to engineer mammalian artificial chromosomes (MACs) as therapeutic vectors: (1) in vitro MAC cloning by enzymatic ligation of the individual MAC components ...
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