Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...

A cell has many ways to regulate gene expression, one of which is the structure of the genome itself; active genes have to be accessible to the cellular machinery to be expressed. The DNA in the ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

Supercoil me! The art of knotted DNA maintenance Supercoiling can keep DNA knots locked in place for long enough that they can be untied by specialised enzymes, a new study says Date: July 5, 2018 ...

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...

The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibers far more powerful ...

Tiny robots could serve all kinds of useful functions, but shrinking their actuators has proven challenging. Now researchers at the University of Wollongong (UOW) in Australia have made artificial ...

Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. A new study by SISSA (Scuola Internazionale ...