A main theory behind the cause of Alzheimer’s disease is the build-up of the protein amyloid-beta in the brain. Researchers from the University of Cincinnati provide evidence suggesting it’s the ...

Problems with mitochondria and energy production are common features of aging. As people grow older, the efficiency of mitochondria often declines. This decline may increase the risk of many diseases, ...

Panelists discuss how amyloid-targeting therapies for Alzheimer disease represent a breakthrough drug class that works by binding to and removing beta-amyloid plaques through various mechanisms, ...

Alzheimer's disease is a form of progressive dementia that we've labored to figure out for decades. Scientists made some headway with the amyloid hypothesis of Alzheimer's disease, but progress is ...

Have we been wrong about what causes Alzheimer's disease? New research suggests yes. For years, the leading theory for the cause of this neurodegeneration was the accumulation of abnormal proteins in ...

Research on Alzheimer's disease is one of the hottest topics in the biological sciences today. In 1992, for instance, two Alzheimer's papers made it into the list of the top 25 cited papers of the ...

The hallmark pathology of Alzheimer's is accumulation of a protein called amyloid in the brain. Many researchers have assumed that these aggregates, or plaques, are simply a byproduct of some other ...

The FDA has convened an advisory panel to discuss the safety and efficacy of Eli Lilly's anti-amyloid antibody drug donanemab. Approval of donanemab could have a modestly positive impact on LLY stock, ...

In the summer of 2024 several groups of scientists published a curious finding: people vaccinated against shingles were less likely to develop dementia than their unvaccinated peers. Two preprints ...