Thousands of people have fled their homes as a brush fire in the Pacific Palisades has grown to more than 17,000 acres Wednesday.

By the time the winds get to the point where the Eaton Fire broke out in Altadena on Jan. 7, it’s not uncommon for them to have less than 5 percent relative humidity, meaning essentially no moisture at all.

The devastating fires that have killed at least five people and forced the evacuations of tens of thousands of residents across the Los Angeles region are driven by Santa Ana winds that blow from the deserts of interior California and Nevada out to the Pacific Ocean.